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The beneficial effects of pomegranate extract in intestinal inflammation


A recent study shows that pomegranate extract, rich in bioactive compounds, could contribute to the prevention of intestinal inflammation.

Pomegranate is a fruit rich in bioactive phenolic compounds such as punicalagins, gallic acid, and ellagic acid derivatives. Many investigations have reported that pomegranate extract (PE) is rich sources of bioactive compounds that possess anticancer, antiviral and anti-inflammatory activities. In addition, polyphenols have been used in the prevention of several diseases such as diabetes cardiovascular and neurodegenerative diseases, cancers and inflammatory bowel diseases (IBDs).

Recently, a collaborative work with several investigators of Italy and Bahrain has studied the beneficial effects of pomegranate extract in intestinal inflammation. They conclude that the potential health benefits of a pomegranate can be mediated by different molecular mechanisms.  The increase in the levels of key proteins induced by the pomegranate extract may contribute to the reduction of oxidative stress with the consequent prevention or reduction of intestinal inflammation. Overall,  their  data  allow  them  to  affirm  that  protective and anti-inflammatory properties of high concentrations of pomegranate  polyphenols  could  contribute,  as  supportive therapy to enhance the effects of the conventional therapeutic strategies to treat cancers and inflammatory bowel diseases (IBDs).

Article: Potential Health Benefits of a Pomegranate Extract, Rich in Phenolic Compounds, in Intestinal Inflammation. https://doi.org/10.2174/1573401317666210222103032